Feb, 2024

Ph.D. positions are available at the Yenepoya Research Center (YRC) in the Translational Neuroscience laboratory headed by Dr. Arnab Datta. We combine various preclinical models (such as Oxygen-Glucose Deprivation and Middle Cerebral Artery Occlusion models) and comparable clinical samples to discover potential therapeutic targets and biomarkers for stoke using a systems biological approach. Stroke is the most debilitating among all neurological disorders ahead of ALzheimer's or Parkinson's Disease and the predominant cause of adult morbidity with limited treatment options. We seek to understand how perturbations in protein expression, protein secretion, and post-translational modifications such as phosphorylation and deamidation mediate neurovascular dysfunction in brain injury and repair. In this pursuit, we use a combination of pharmacological, biochemical, proteomics, bioinformatics, and molecular biological tools. It is expected that as a member of this lab, one will have an opportunity to be exposed to all these areas. They value a vibrant and collaborative environment where lab members share ideas, reagents, and expertise and desire to work on understanding the pathophysiology of ischemic stroke.

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The current project is related to the development of a state-of-the-art rodent immunotherapeutics laboratory where efficacy studies will be performed using monoclonal antibodies against degenerative protein deamidation in animal models of acute ischemic stroke. The project will involve academic exchanges with collaborators from India and abroad such as Brock University, Canada, and the University of Auckland, New Zealand.

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Funding: GST K-FIST L2 scheme for infrastructure development and Yenepoya (Deemed to be University)

Qualifications:

M.Pharm in Pharmacology/M.Tech/ M.Sc. with relevant specialization with 1 year of suitable industrial or academic experience. Experience in animal dosing, cannulation, and survival surgeries will be preferred. Qualification in GPAT/CSIR-NET/DBT-JRF/ICMR-JRF/UGC-JRF/GATE is highly desirable.

Candidates with own fellowship such as INSPIRE are encouraged to apply. Having publications in peer-reviewed journals will be an added advantage.

Other requirements include the ability to work independently following training, strong verbal and written communication skills in English, strong motivation, and most importantly a high level of creativity and enthusiasm for science

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To Apply:

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Interested applicants should send a CV, names of 2 references, and a summary (max. 1 page, font: 11, Arial) of their future career goals to Dr. Arnab Datta: arnabdatta@yenepoya.edu.in. Please write "PhD application" in the subject header.